Article
The sevenless signalling cassette mediates Drosophila EGF receptor function during epidermal development.
Development (Cambridge, England) - 1 Mar 1994
Diaz-Benjumea F J, Hafen E
Abstract excerpt
In Drosophila, Drk, an SH2 adaptor protein, Sos, a putative activator of Ras1, Ras1, raf and rolled/MAP kinase have been shown to be required for signalling from the sevenless and the torso receptor tyrosine kinase. From these studies, it was unclear whether these components act in a single linea...
Topics
- Animals
- Cell Differentiation
- Drosophila
- Drosophila Proteins
- Epidermis
- ErbB Receptors
- Eye Proteins
- Genes, Insect
- Membrane Glycoproteins
- Morphogenesis
- Mutation
- Phenotype
- Receptor Protein-Tyrosine Kinases
- Signal Transduction
- Wings, Animal