Article
The sevenless signalling cassette mediates Drosophila EGF receptor function during epidermal development.
Development (Cambridge, England) - 1 Mar 1994
Diaz-Benjumea F J, Hafen E
Abstract excerpt
In Drosophila, Drk, an SH2 adaptor protein, Sos, a putative activator of Ras1, Ras1, raf and rolled/MAP kinase have been shown to be required for signalling from the sevenless and the torso receptor tyrosine kinase. From these studies, it was unclear whether these components act in a single linear pathway as suggested by the genetic analysis or whether different components serve to integrate different signals. We...
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