Article
Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila.
The EMBO journal - 1 Jun 1995
Raabe T, Olivier J P, Dickson B, Liu X, Gish G D, Pawson T, Hafen E
Abstract excerpt
The Drk SH3-SH2-SH3 adaptor protein has been genetically identified in a screen for rate-limiting components acting downstream of the Sevenless (Sev) receptor tyrosine kinase in the developing eye of Drosophila. It provides a link between the activated Sev receptor and Sos, a guanine nucleotide r...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- DNA, Complementary
- Drosophila
- Drosophila Proteins
- Eye Proteins
- Genes, Insect
- In Vitro Techniques
- Insect Hormones
- Membrane Glycoproteins
- Membrane Proteins
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Receptor Protein-Tyrosine Kinases
- Signal Transduction