Molecular analysis of the Drosophila EGF receptor homolog reveals that several genetically defined classes of alleles cluster in subdomains of the receptor protein.

doi:10.1093/genetics/137.2.531

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Article

Molecular analysis of the Drosophila EGF receptor homolog reveals that several genetically defined classes of alleles cluster in subdomains of the receptor protein.

Genetics - 1 Jun 1994

Clifford R, Schüpbach T

Abstract excerpt

Mutations in the torpedo gene, which encodes the fruitfly homolog of the epidermal growth factor receptor (DER), disrupt a variety of developmental processes in Drosophila. These include the survival of certain embryonic ectodermal tissues, the proliferation of the imaginal discs, the morphogenes...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Conserved Sequence
Crosses, Genetic
Drosophila melanogaster
Embryo, Nonmammalian
ErbB Receptors
Exons
Female
Genes, Insect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Lethal

Genetic Complementation Test

Humans

Male

Molecular Sequence Data

Mosaicism

Source

Open in PubMed Open full text

Identifiers

PMID: 8070664
DOI: 10.1093/genetics/137.2.531
PMCID: PMC1205976

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8070664-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Molecular analysis of the Drosophila EGF receptor homolog reveals that several genetically defined classes of alleles cluster in subdomains of the receptor protein.PMID 8070664Read ↗

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Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling.Semantic proximity Read ↗

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