Article
Calcium ionophore increases amyloid beta peptide production by cultured cells.
Biochemistry - 19 Apr 1994
Querfurth H W, Selkoe D J
Abstract excerpt
Amyloid beta peptide (A beta) is released into the media of a variety of cells in culture during normal metabolism. The discovery of several missense mutations within or flanking the A beta region of the beta amyloid precursor protein (beta APP) in familial Alzheimer's disease provides strong evi...
Topics
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Caffeine
- Calcimycin
- Calcium
- Cell Line
- DNA, Complementary
- Enzyme Activation
- Glycosylation
- Homeostasis
- Humans
- Immunosorbent Techniques
- Kidney