Tumor necrosis factor polymorphism in multiple sclerosis: no additional association independent of HLA.

doi:10.1016/0165-5728(94)90133-3

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Article

Tumor necrosis factor polymorphism in multiple sclerosis: no additional association independent of HLA.

Journal of neuroimmunology - 1 Apr 1994

Roth M P, Nogueira L, Coppin H, Clanet M, Clayton J, Cambon-Thomsen A

Abstract excerpt

In order to investigate whether genes coding for tumor necrosis factors (TNF) contribute to the pathogenesis of multiple sclerosis (MS) and also whether they have a non-random association with the MS associated HLA-DRB1*1501-DQA1*0102-DQB1*0602 haplotype, 40 MS patients and their parents were cha...

Topics

Alleles
Base Sequence
DNA, Satellite
HLA Antigens
Haplotypes
Humans
Molecular Probes
Molecular Sequence Data
Multiple Sclerosis
Polymerase Chain Reaction
Polymorphism, Genetic
Tumor Necrosis Factor-alpha

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