Female specific hyperactivity in S100 beta transgenic mice does not habituate in open-field.

doi:10.1016/0166-4328(93)90157-l

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Article

Female specific hyperactivity in S100 beta transgenic mice does not habituate in open-field.

Behavioural brain research - 31 Dec 1993

Gerlai R, Roder J

Abstract excerpt

S100 beta, a calcium-binding brain specific protein, may affect brain development and long-term potentiation. Its gene maps to a region of chromosome 21 duplicated in Down's Syndrome (DS), and its levels are elevated in DS. To test the hypothesis that elevated S100 beta levels cause brain dysfunc...

Topics

Animals
Blotting, Southern
Down Syndrome
Exploratory Behavior
Female
Genotype
Habituation, Psychophysiologic
Humans
Male
Mice
Mice, Transgenic
Motor Activity
S100 Proteins
Sex Characteristics
Time Factors

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