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Article

The role of the p50 and p65 subunits of NF-kappa B in the recognition of cognate sequences.

The New biologist - 1 Mar 1991

Urban M B, Baeuerle P A

Abstract excerpt

An important regulatory element for expression of the MHC class I gene H-2Kb is a palindromic 11-bp enhancer sequence, 5'-GGGGATTCCCC-3', which was shown to interact with the constitutive factor(s) KBF1/H2TF1 and the inducible nuclear factor NF-kappa B, a multisubunit transcription activator. Recent data from molecular cloning and biochemical analyses of KBF1 and NF-kappa B have shown that KBF1 corresponds to the...

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PMID: 1878350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The role of the p50 and p65 subunits of NF-kappa B in the recognition of cognate sequences.PMID 1878350Read ↗

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Structural and functional analysis of NF-kappa B. Determinants of DNA binding specificity and protein interaction.Semantic proximity Read ↗

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Recognition sequence of a highly conserved DNA binding protein RBP-J kappa.Semantic proximity Read ↗

A mutant Rel-homology domain promotes transcription by p50/NFkappaB1.Semantic proximity Read ↗

cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B.Semantic proximity Read ↗

Novel sites in the p65 subunit of NF-kappaB interact with TFIIB to facilitate NF-kappaB induced transcription.Semantic proximity Read ↗

A set of inducible genes expressed by activated human monocytic and endothelial cells contain kappa B-like sites that specifically bind c-Rel-p65 heterodimers.Semantic proximity Read ↗

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.Semantic proximity Read ↗

Genomic organization of the gene encoding the p65 subunit of NF-kappa B: multiple variants of the p65 protein may be generated by alternative splicing.Semantic proximity Read ↗

Mutational analysis of the kinetics and thermodynamics of transcription factor NF-kappaB homodimerisation.Semantic proximity Read ↗

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