Article
The role of the p50 and p65 subunits of NF-kappa B in the recognition of cognate sequences.
The New biologist - 1 Mar 1991
Urban M B, Baeuerle P A
Abstract excerpt
An important regulatory element for expression of the MHC class I gene H-2Kb is a palindromic 11-bp enhancer sequence, 5'-GGGGATTCCCC-3', which was shown to interact with the constitutive factor(s) KBF1/H2TF1 and the inducible nuclear factor NF-kappa B, a multisubunit transcription activator. Rec...
Topics
- Base Sequence
- Binding, Competitive
- DNA
- Electrophoresis, Polyacrylamide Gel
- Enhancer Elements, Genetic
- Genes, MHC Class I
- H-2 Antigens
- Humans
- Molecular Sequence Data
- Mutation
- NF-kappa B
- Oligonucleotides
- Spermine