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Article

Response of dynamic structure to removal of a disulfide bond: normal mode refinement of C77A/C95A mutant of human lysozyme.

Protein science : a publication of the Protein Society - 1 Jan 1994

Kidera A, Inaka K, Matsushima M, Go N

Abstract excerpt

In order to investigate the response of dynamic structure to removal of a disulfide bond, the dynamic structure of human lysozyme has been compared to its C77A/C95A mutant. The dynamic structures of the wild type and mutant are determined by normal mode refinement of 1.5-A-resolution X-ray data. The C77A/C95A mutant shows an increase in apparent fluctuations at most residues. However, most of the change...

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PMID: 8142902
DOI: 10.1002/pro.5560030112
PMCID: PMC2142470

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