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Article

Reversible disassembly of an intestinal epithelial monolayer by prolonged exposure to phorbol ester.

The American journal of physiology - 1 Feb 1994

Hecht G, Robinson B, Koutsouris A

Abstract excerpt

This article describes a model of reversible disassembly of a cultured human intestinal epithelial monolayer by prolonged exposure to the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA). Prolonged phorbol ester exposure reduces protein kinase C (PKC) levels in numerous cell types includi...

Topics

Actins
Down-Regulation
Electric Conductivity
Humans
Intercellular Junctions
Intestinal Mucosa
Phenotype
Protein Kinase C
Proteins
Tetradecanoylphorbol Acetate
Time Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8141294
DOI: 10.1152/ajpgi.1994.266.2.G214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8141294-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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