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Article

Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair

2018-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Intestinal ischemic injury results sloughing of the mucosal epithelium leading to host sepsis and death unless the mucosal barrier is rapidly restored. Neonatal necrotizing enterocolitis (NEC) and volvulus in infants is associated with intestinal ischemia, sepsis and high mortality rates. We have characterized intestinal ischemia/ repair using a highly translatable porcine model in which juvenil...

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Identifiers and source

Literature Corpus work
41909248-03e7-580d-82d8-c774209a4fd4
DOI
10.1101/361352
Open publication

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