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Article

Ribosomal frameshifting efficiency and gag/gag-pol ratio are critical for yeast M1 double-stranded RNA virus propagation.

Journal of virology - 1 Jun 1992

Dinman J D, Wickner R B

Abstract excerpt

About 1.9% of ribosomes translating the gag open reading frame of the yeast L-A double-stranded RNA virus positive strand undergo a -1 frameshift and continue translating in the pol open reading frame to make a 170-kDa gag-pol fusion protein. The importance of frameshifting efficiency for viral propagation was tested in a system where the M1 (killer toxin-encoding) satellite RNA is supported by a full-length L-A...

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Identifiers

PMID: 1583726
DOI: 10.1128/JVI.66.6.3669-3676.1992
PMCID: PMC241150

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