Article
Inherited enhancement of hydroxyl radical generation and lipid peroxidation in the S strain rats results in DNA rearrangements, degenerative diseases, and premature aging.
Biochemical and biophysical research communications - 15 Mar 1994
Salganik R I, Solovyova N A, Dikalov S I, Grishaeva O N, Semenova L A, Popovsky A V
Abstract excerpt
Previously by selection and inbreeding of Wistar rats susceptible or resistant to the cataractogenic effect of galactose the S and R rat strains differing in the intensity of hexose transport into the animal cells were developed. High level of OH-radical generation and enhanced lipid peroxidation are revealed in the liver and myocardium of the S rats in contrast to the R rats. Data are obtained supporting the...
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