Article
Analysis of mitochondrial DNA somatic mutations in OXYS and Wistar strain rats.
Biochemistry. Biokhimiia - 1 Apr 2009
Rotskaya U N, Rogozin I B, Vasyunina E A, Kolosova N G, Malyarchuk B A, Nevinsky G A, Sinitsyna O I
Abstract excerpt
Rats of the OXYS strain are sensitive to oxidative stress and serve as a biological model of premature aging. We have compared spectra of somatic mutations in a control region of mtDNA from the liver of the OXYS rat strain and of Wistar rats as a control. The majority of nucleotide substitutions...
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