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Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathology

21 Mar 2023

Abstract excerpt

Reactive oxygen species (ROS) is a term that defines a group of unstable compounds derived from exogenous sources or endogenous metabolism. Under physiological conditions, low levels of ROS play a key role in the regulation of signal transduction- or transcription-mediated cellular responses. In contrast, excessive and uncontrolled loading of ROS results in a pathological state known as oxidative stress (OS), a...

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PMID: 36958540
DOI: 10.1016/j.mad.2023.111802

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