Article
C. elegans serine-threonine kinase KIN-29 modulates TGFbeta signaling and regulates body size formation.
BMC developmental biology - 19 Apr 2005
Maduzia Lisa L, Roberts Andrew F, Wang Huang, Lin Xia, Chin Lena J, Zimmerman Cole M, Cohen Stephen, Feng Xin-Hua, Padgett Richard W
Abstract excerpt
BACKGROUND: In C. elegans there are two well-defined TGFbeta-like signaling pathways. The Sma/Mab pathway affects body size morphogenesis, male tail development and spicule formation while the Daf pathway regulates entry into and exit out of the dauer state. To identify additional factors that modulate TGFbeta signaling in the Sma/Mab pathway, we have undertaken a genetic screen for small animals and have...
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