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Article

A parent-twin study of plasma levels of histidine-rich glycoprotein (HRG).

Thrombosis and haemostasis - 15 Nov 1993

Boomsma D I, Hennis B C, van Wees A G, Frants R R, Kluft C

Abstract excerpt

Histidine-rich glycoprotein (HRG) is a non-enzymatic glycoprotein that acts as a modulator of several plasma proteins involved in coagulation and fibrinolysis. The contributions of genetic and environmental influences to inter-individual variation in plasma levels of HRG were studied in 160 Dutch families consisting of adolescent twin pairs and their parents. Results showed that 69% of the variance in plasma HRG...

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Source

Identifiers

PMID: 8128444

Genes

HRG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

A parent-twin study of plasma levels of histidine-rich glycoprotein (HRG).PMID 8128444Read ↗

An amino acid polymorphism in histidine-rich glycoprotein (HRG) explains 59% of the variance in plasma HRG levels.Semantic proximity Read ↗

High levels of histidine-rich glycoprotein and thrombotic diathesis. Report of two unrelated families.Semantic proximity Read ↗

Histidine-rich glycoprotein polymorphism and pregnancy outcome: a pilot study.Semantic proximity Read ↗

Identification and genetic analysis of a common molecular variant of histidine-rich glycoprotein with a difference of 2kD in apparent molecular weight.Semantic proximity Read ↗

Histidine-rich glycoprotein changes during pregnancy in a woman with genetically transmitted high levels of the protein and thrombotic diathesis.Semantic proximity Read ↗

Histidine-rich glycoprotein is not associated with thrombosis in a UK Biobank Mendelian randomisation analysisSemantic proximity Read ↗

Hereditary increase of plasma histidine-rich glycoprotein associated with abnormal heparin binding (HRG Eindhoven).Semantic proximity Read ↗

A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.Semantic proximity Read ↗

Enhanced blood coagulation and fibrinolysis in mice lacking histidine-rich glycoprotein (HRG).Semantic proximity Read ↗

Prevalence of elevated histidine-rich glycoprotein in patients with thrombophilia--a study of 695 patients.Semantic proximity Read ↗

Unique insertion/deletion polymorphisms within histidine-rich region of histidine-rich glycoprotein in Thoroughbred horsesSemantic proximity Read ↗

Ovarian response is affected by a specific histidine-rich glycoprotein polymorphism: a preliminary study.Semantic proximity Read ↗

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