A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.

doi:10.1111/j.1365-2141.1995.tb08423.x

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Article

A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.

British journal of haematology - 1 Apr 1995

Hennis B C, Van Boheemen P A, Koeleman B P, Boomsma D I, Engesser L, Van Wees A G, Novakova I, Brommer E J, Kluft C

Abstract excerpt

Recent studies describe families with both elevated plasma HRG levels and thrombosis. In order to study the possibility that allelic variants of the HRG locus are associated with differences in HRG level, we studied linkage between HRG levels and a dinucleotide repeat polymorphism in a Dutch family which was selected on the presence of both thrombosis and elevated plasma HRG levels. No other known risk factors...

Topics

Aged
Alleles
Base Sequence
Blood Coagulation
Female
Genetic Linkage
Glycoproteins
Humans
Male
Middle Aged
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pedigree

Polymorphism, Genetic

Proteins

Repetitive Sequences, Nucleic Acid

Thrombosis

Histidine-Rich Glycoprotein

Source

Open in PubMed

Identifiers

PMID: 7772521
DOI: 10.1111/j.1365-2141.1995.tb08423.x

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7772521-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.PMID 7772521Read ↗

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