Article
A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.
British journal of haematology - 1 Apr 1995
Hennis B C, Van Boheemen P A, Koeleman B P, Boomsma D I, Engesser L, Van Wees A G, Novakova I, Brommer E J, Kluft C
Abstract excerpt
Recent studies describe families with both elevated plasma HRG levels and thrombosis. In order to study the possibility that allelic variants of the HRG locus are associated with differences in HRG level, we studied linkage between HRG levels and a dinucleotide repeat polymorphism in a Dutch family which was selected on the presence of both thrombosis and elevated plasma HRG levels. No other known risk factors...
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