Article
Ovarian response is affected by a specific histidine-rich glycoprotein polymorphism: a preliminary study.
Reproductive biomedicine online - 1 Jan 2015
Nordqvist Sarah, Kårehed Karin, Skoog Svanberg Agneta, Menezes Judith, Åkerud Helena
Abstract excerpt
Genetic polymorphisms involved in angiogenesis, apoptosis and chemokine signalling are associated with varying ovarian response and oocyte quality. The protein, histidine-rich glycoprotein (HRG), is involved in these processes, but its effect on ovarian response in IVF has not been previously studied. A single nucleotide polymorphism (SNP) in the HRG gene (C633T) seems to affect pregnancy results in IVF. Women...
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