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Article

Hereditary increase of plasma histidine-rich glycoprotein associated with abnormal heparin binding (HRG Eindhoven).

Thrombosis and haemostasis - 20 Dec 1993

Hoffmann J J, Hennis B C, Kluft C, Vijgen M

Abstract excerpt

Plasma histidine-rich glycoprotein (HRG) was found to be persistently increased in a patient with a history of recurrent arterial thromboembolic events. The mean concentration was 270% of normal pooled plasma. Increased HRG was found in eight of the 17 relatives studied, but none of them has experienced thrombo-embolism yet. Apparently, increased HRG was hereditary with autosomal dominant inheritance. A...

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Identifiers

PMID: 8165607

Genes

HRG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 8 closest

Hereditary increase of plasma histidine-rich glycoprotein associated with abnormal heparin binding (HRG Eindhoven).PMID 8165607Read ↗

High levels of histidine-rich glycoprotein and thrombotic diathesis. Report of two unrelated families.Semantic proximity Read ↗

Identification and genetic analysis of a common molecular variant of histidine-rich glycoprotein with a difference of 2kD in apparent molecular weight.Semantic proximity Read ↗

Histidine-rich glycoprotein changes during pregnancy in a woman with genetically transmitted high levels of the protein and thrombotic diathesis.Semantic proximity Read ↗

A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.Semantic proximity Read ↗

A parent-twin study of plasma levels of histidine-rich glycoprotein (HRG).Semantic proximity Read ↗

Prevalence of elevated histidine-rich glycoprotein in patients with thrombophilia--a study of 695 patients.Semantic proximity Read ↗

An amino acid polymorphism in histidine-rich glycoprotein (HRG) explains 59% of the variance in plasma HRG levels.Semantic proximity Read ↗

Familial early-onset deep venous thrombosis associated with a novel HRG mutation.Semantic proximity Read ↗

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