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Article

High levels of histidine-rich glycoprotein and thrombotic diathesis. Report of two unrelated families.

Thrombosis research - 1 Feb 1993

Castaman G, Ruggeri M, Burei F, Rodeghiero F

Abstract excerpt

Two new families with history of thrombosis and high levels of histidine-rich glycoprotein (HRG) are described. The propositus of family 1 died of massive pulmonary embolism at age 34. Among his relatives, the mother and the maternal grandmother had suffered from deep and superficial vein thrombosis in their youth. A maternal aunt had several episodes of superficial vein thrombosis (SVT). High levels of HRG were...

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Identifiers

PMID: 8475479
DOI: 10.1016/0049-3848(93)90027-l

Genes

HRG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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High levels of histidine-rich glycoprotein and thrombotic diathesis. Report of two unrelated families.PMID 8475479Read ↗

A parent-twin study of plasma levels of histidine-rich glycoprotein (HRG).Semantic proximity Read ↗

Hereditary increase of plasma histidine-rich glycoprotein associated with abnormal heparin binding (HRG Eindhoven).Semantic proximity Read ↗

Histidine-rich glycoprotein changes during pregnancy in a woman with genetically transmitted high levels of the protein and thrombotic diathesis.Semantic proximity Read ↗

Enhanced blood coagulation and fibrinolysis in mice lacking histidine-rich glycoprotein (HRG).Semantic proximity Read ↗

Prevalence of elevated histidine-rich glycoprotein in patients with thrombophilia--a study of 695 patients.Semantic proximity Read ↗

A newborn with hereditary haemorrhagic telangiectasia and an unusually severe phenotype.Semantic proximity Read ↗

Identification and genetic analysis of a common molecular variant of histidine-rich glycoprotein with a difference of 2kD in apparent molecular weight.Semantic proximity Read ↗

An amino acid polymorphism in histidine-rich glycoprotein (HRG) explains 59% of the variance in plasma HRG levels.Semantic proximity Read ↗

A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis.Semantic proximity Read ↗

Histidine-rich glycoprotein is not associated with thrombosis in a UK Biobank Mendelian randomisation analysisSemantic proximity Read ↗

FV HR2 haplotype as additional inherited risk factor for deep vein thrombosis in individuals with a high-risk profile.Semantic proximity Read ↗

Histidine-rich glycoprotein (HRG) Tokushima 2: novel HRG deficiency, molecular and cellular characterization.Semantic proximity Read ↗

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