Article
Identification and genetic analysis of a common molecular variant of histidine-rich glycoprotein with a difference of 2kD in apparent molecular weight.
Thrombosis and haemostasis - 1 Dec 1995
Hennis B C, van Boheemen P A, Wakabayashi S, Koide T, Hoffmann J J, Kievit P, Dooijewaard G, Jansen J G, Kluft C
Abstract excerpt
Two forms of histidine-rich glycoprotein (HRG) were detected on SDS-PAGE by silver staining and immunoblotting after isolation of the protein from pooled plasma using immuno-affinity chromatography followed by chromatography with heparin-Sepharose. Both forms were single-chain molecules and the apparent molecular weights of form 1 and form 2 were 77 kD and 75 kD respectively. Mendelian inheritance of both HRG...
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