Article
Identification and genetic analysis of a common molecular variant of histidine-rich glycoprotein with a difference of 2kD in apparent molecular weight.
Thrombosis and haemostasis - 1 Dec 1995
Hennis B C, van Boheemen P A, Wakabayashi S, Koide T, Hoffmann J J, Kievit P, Dooijewaard G, Jansen J G, Kluft C
Abstract excerpt
Two forms of histidine-rich glycoprotein (HRG) were detected on SDS-PAGE by silver staining and immunoblotting after isolation of the protein from pooled plasma using immuno-affinity chromatography followed by chromatography with heparin-Sepharose. Both forms were single-chain molecules and the a...
Topics
- Amino Acid Sequence
- Base Sequence
- Blood Proteins
- Case-Control Studies
- Exons
- Genetic Code
- Genetic Variation
- Genotype
- Glycoproteins
- Humans
- Molecular Sequence Data
- Molecular Weight
- Pedigree
- Phenotype
- Polymorphism, Genetic