Article
Histidine-rich glycoprotein polymorphism and pregnancy outcome: a pilot study.
Reproductive biomedicine online - 1 Aug 2011
Nordqvist Sarah, Kårehed Karin, Stavreus-Evers Anneli, Akerud Helena
Abstract excerpt
Histidine-rich glycoprotein (HRG) is involved in fibrinolysis and coagulation, the immune system and angiogenesis. These processes are all crucial in establishing and maintaining pregnancy. The primary aim of this pilot study was to determine if HRG affects pregnancy outcome. The secondary aim was to investigate if a specific genetic polymorphism (rs9898 C/T) in the HRG gene is associated with pregnancy results....
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