Article
An SRY-related sequence on the marsupial X chromosome: implications for the evolution of the mammalian testis-determining gene.
Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1994
Foster J W, Graves J A
Abstract excerpt
The SRY gene on the human, mouse, and marsupial Y chromosomes is the testis-determining gene that initiates male development in mammals. The SRY protein has a DNA-binding domain (high mobility group or HMG box) similar to those found in the high-mobility-group proteins. SRY is specific for the Y chromosome, but many autosomal genes have been identified that possess a similar HMG box region; those with the most...
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