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Article

Sox genes find their feet.

Current opinion in genetics & development - 1 Jun 1997

Pevny L H, Lovell-Badge R

Abstract excerpt

The identification of the mammalian testis-determining factor, SRY, led to the description of a new class of genes encoding transcription factors, the SOX gene family. SOX proteins display properties of both classical transcription factors and architectural components of chromatin. The dynamic an...

Topics

Animals
Chromosome Mapping
DNA-Binding Proteins
Developmental Biology
Gene Expression
High Mobility Group Proteins
Humans
Molecular Biology
Multigene Family
Mutation
Nuclear Proteins
Sequence Homology
Transcription Factors

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Source

Identifiers

PMID: 9229109
DOI: 10.1016/s0959-437x(97)80147-5

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9229109-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sox genes find their feet.PMID 9229109Read ↗

SOX Genes and Their Role in Disorders of Sex DevelopmentSemantic proximity Read ↗

Sry and Sox9: mammalian testis-determining genesSemantic proximity Read ↗

Sox proteins: regulators of cell fate specification and differentiationSemantic proximity Read ↗

All purpose Sox: The many roles of Sox proteins in gene expressionSemantic proximity Read ↗

Regulatory roles for SOX11 in development, stem cells and cancerSemantic proximity Read ↗

The SOX gene family: function and regulation in testis determination and male fertility maintenanceSemantic proximity Read ↗

Whatever happened to SRY?Semantic proximity Read ↗

Diverse Regulation but Conserved Function: SOX9 in Vertebrate Sex DeterminationSemantic proximity Read ↗

Two redundant transcription factor binding sites in a single enhancer are essential for mammalian sex determination.Semantic proximity Read ↗

Sry and SoxE genes: How they participate in mammalian sex determination and gonadal development?Semantic proximity Read ↗

The Sex-Determining Factors SRY and SOX9 Regulate Similar Target Genes and Promote Testis Cord Formation during Testicular DifferentiationSemantic proximity Read ↗

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9Semantic proximity Read ↗

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