Article
Genetic studies on dynamin function in Drosophila.
Journal of neurogenetics - 1 Dec 1993
Ramaswami M, Rao S, van der Bliek A, Kelly R B, Krishnan K S
Abstract excerpt
The shibire(ts2) mutation of Drosophila melanogaster causes a temperature sensitive inhibition of endocytosis; this in turn leads to synaptic-vesicle depletion and consequent paralysis. Heat-pulses delivered during development of shibire(ts2) individuals affect the morphology of a number of adult...
Topics
- Animals
- Chromosome Mapping
- Drosophila Proteins
- Drosophila melanogaster
- Dynamins
- Endocytosis
- Female
- GTP Phosphohydrolases
- Genes, Suppressor
- Genetic Carrier Screening
- Genetic Linkage
- Hot Temperature
- Male
- Mutation
- Nervous System Physiological Phenomena
- Paralysis
- Suppression, Genetic
- Synaptic Vesicles
