Article
Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic.
Nature - 30 May 1991
van der Bliek A M, Meyerowitz E M
Abstract excerpt
Temperature-sensitive paralysis is the most striking defect of adult Drosophila carrying the shibire mutation. This is believed to be due to a reversible block of endocytosis, which prevents membrane cycling and thus depletes synaptic vesicles. The shibire mutation also affects many tissues outside the nervous system. We have now mapped and characterized the shibire gene. A 275-kilobase yeast artificial...
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