Article
Overexpressing temperature-sensitive dynamin decelerates phototransduction and bundles microtubules in Drosophila photoreceptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Nov 2009
Gonzalez-Bellido Paloma T, Wardill Trevor J, Kostyleva Ripsik, Meinertzhagen Ian A, Juusola Mikko
Abstract excerpt
shibire(ts1), a temperature-sensitive mutation of the Drosophila gene encoding a Dynamin orthologue, blocks vesicle endocytosis and thus synaptic transmission, at elevated, or restrictive temperatures. By targeted Gal4 expression, UAS-shibire(ts1) has been used to dissect neuronal circuits. We investigated the effects of UAS-shibire(ts1) overexpression in Drosophila photoreceptors at permissive (19 degrees C) and...
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