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Article

Probable mechanisms underlying interallelic complementation and temperature-sensitivity of mutations at the shibire locus of Drosophila melanogaster.

Genetics - 1 Jun 1998

Grant D, Unadkat S, Katzen A, Krishnan K S, Ramaswami M

Abstract excerpt

The shibire locus of Drosophila melanogaster encodes dynamin, a GTPase required for the fission of endocytic vesicles from plasma membrane. Biochemical studies indicate that mammalian dynamin is part of a complex containing multiple dynamin subunits and other polypeptides. To gain insight into sequences of dynamin critical for its function, we have characterized in detail a collection of conditional and lethal...

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Identifiers

PMID: 9611210
DOI: 10.1093/genetics/149.2.1019
PMCID: PMC1460189

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Probable mechanisms underlying interallelic complementation and temperature-sensitivity of mutations at the shibire locus of Drosophila melanogaster.PMID 9611210Read ↗

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