Article
Probable mechanisms underlying interallelic complementation and temperature-sensitivity of mutations at the shibire locus of Drosophila melanogaster.
Genetics - 1 Jun 1998
Grant D, Unadkat S, Katzen A, Krishnan K S, Ramaswami M
Abstract excerpt
The shibire locus of Drosophila melanogaster encodes dynamin, a GTPase required for the fission of endocytic vesicles from plasma membrane. Biochemical studies indicate that mammalian dynamin is part of a complex containing multiple dynamin subunits and other polypeptides. To gain insight into se...
Topics
- Alleles
- Animals
- Drosophila Proteins
- Drosophila melanogaster
- Dynamins
- GTP Phosphohydrolases
- Genes, Dominant
- Genes, Lethal
- Genes, Recessive
- Genetic Complementation Test
- Mutation
- Paralysis
- Phenotype
- Temperature