Article
Decreased expression of liver glutathione peroxidase in Long-Evans cinnamon mutant rats predisposed to hepatitis and hepatoma.
Hepatology (Baltimore, Md.) - 1 Mar 1994
Suemizu H, Yoshimura S, Takeichi N, Moriuchi T
Abstract excerpt
The Long-Evans Cinnamon rat is a mutant strain that contracts hereditary hepatitis and, eventually, spontaneous hepatoma. Recently, abnormal copper accumulations in Long-Evans Cinnamon rat livers were shown to be genetically linked to the development of hepatitis. Because reduced glutathione and...
Topics
- Animals
- Blotting, Northern
- Genetic Predisposition to Disease
- Glutathione Peroxidase
- Hepatitis, Animal
- Kidney
- Liver
- Liver Neoplasms, Experimental
- Male
- Rats
- Rats, Inbred Strains
- Rats, Mutant Strains