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Article

Hepatocyte transplantation in the Long Evans Cinnamon rat model of Wilson's disease.

Cell transplantation - 1 Jan 2006

Park Seon Mee, Vo Kim, Lallier Michel, Cloutier Alexis-Simon, Brochu Pierre, Alvarez Fernando, Martin Steven R

Abstract excerpt

Wilson's disease (WD), caused by a mutation in the P-type copper transporting ATPase (Atp7b) gene, results in excessive accumulation of copper in the liver. Long Evans Cinnamon rats (LEC) bear a mutation in the atp7b gene and share clinical characteristics of human WD. To explore hepatocyte transplantation (HT) as therapy for metabolic liver diseases, 8-week-old LEC rats (n = 12) were transplanted by intrasplenic...

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Identifiers

PMID: 16700326
DOI: 10.3727/000000006783982188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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