Malignant transformation of human bronchial epithelial cells by radon-simulated alpha-particles.

doi:10.1093/carcin/15.3.431

Back to search

Article

Malignant transformation of human bronchial epithelial cells by radon-simulated alpha-particles.

Carcinogenesis - 1 Mar 1994

Hei T K, Piao C Q, Willey J C, Thomas S, Hall E J

Abstract excerpt

Epidemiological studies have shown that inhalation of radon is associated with an increased risk for bronchogenic carcinoma in uranium miners. These alpha-emitting radon daughters also represent the largest component of background radiation to the general public. In the present study, the oncogen...

Topics

Animals
Base Sequence
Bronchi
Cell Line, Transformed
Cell Transformation, Neoplastic
Genes, ras
Humans
Mice
Mice, Nude
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Radiation Dosage
Radon Daughters
Tetradecanoylphorbol Acetate

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.