Article
Malignant transformation of immortalized human bronchial epithelial cells by asbestos fibers.
Environmental health perspectives - 1 Sept 1997
Hei T K, Wu L J, Piao C Q
Abstract excerpt
Although asbestos is a well-established lung carcinogen, there currently is no suitable human cell model in which to examine the underlying cellular and molecular changes associated with fiber-mediated bronchial carcinogenesis. Using a recently established transformation model based on a human papillomavirus-immortalized human bronchial epithelial cell line, we successfully transformed these BEP2D cells after a...
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