Article
[Liver cirrhosis associated with alpha 1-antitrypsin deficiency].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jan 1994
Miyake K, Wakashima M
Abstract excerpt
alpha 1-antitrypsin (alpha 1-AT) is a glycoprotein called an acute phase reactant, which increases in blood in a variety of inflammations. alpha 1-AT deficiency with an inherited remarkable reduction of alpha 1-AT in blood has two major disorders, pulmonary emphysema and liver diseases, particularly an infantile cirrhosis. It is of great interest that each disorder has peculiar mechanisms based on an imbalance...
Topics
- Adult
- Genetic Variation
- Humans
- Liver Cirrhosis
- Phenotype
- Polymorphism, Genetic
- alpha 1-Antitrypsin
- alpha 1-Antitrypsin Deficiency