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Article

[Alpha-1-antitrypsin deficiency].

Medecine sciences : M/S - 1 Oct 2014

Bouchecareilh Marion

Abstract excerpt

Alpha-1-antitrypsin (α1AT) deficiency is a genetic disorder that manifests as pulmonary emphysema and liver cirrhosis. α1AT deficiency is the most common genetic cause of liver disease in children and also an underappreciated cause of liver disease in adults. The prevalence in the general population in Western Europe is approximately 1 in 2,000. The most common and severe deficiency allele is the Z variant (two...

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PMID: 25311024
DOI: 10.1051/medsci/20143010016

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Source receipt: pubmed, retrieved 7 Sept 2026.

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