Article
Alpha 1-antitrypsin deficiency: an overview.
Acta clinica Belgica - 1 Jan 1993
van Steenbergen W
Abstract excerpt
1. alpha 1-antitrypsin is an antiprotease that inhibits the neutrophil elastase enzyme, and belongs to a family of structurally related serine proteinase inhibitors (serpins). Its methionine358 residue determines the specificity for elastase. 2. The normal M-type alpha 1-antitrypsin is mainly syn...
Topics
- Adult
- Alleles
- Heterozygote
- Humans
- Infant, Newborn
- Liver Diseases
- Liver Failure
- Molecular Structure
- Pulmonary Emphysema
- Smoking
- alpha 1-Antitrypsin
- alpha 1-Antitrypsin Deficiency
