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Article

Substitution rate variation among sites in hypervariable region 1 of human mitochondrial DNA.

Journal of molecular evolution - 1 Dec 1993

Wakeley J

Abstract excerpt

More than an order of magnitude difference in substitution rate exists among sites within hypervariable region 1 of the control region of human mitochondrial DNA. A two-rate Poisson mixture and a negative binomial distribution are used to describe the distribution of the inferred number of changes per nucleotide site in this region. When three data sets are pooled, however, the two-rate model cannot explain the...

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PMID: 8114114
DOI: 10.1007/BF00182747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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