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Article

Hypervariable sites in the mtDNA control region are mutational hotspots.

American journal of human genetics - 1 Oct 2000

Stoneking M

Abstract excerpt

Hypervariable sites in human mtDNA are readily identified in evolutionary studies and are usually assumed to represent mutational hotspots. Recently, an alternative hypothesis was proposed that holds that hypervariable sites may instead reflect ancient mtDNA mutations that have been "shuffled" among different lineages via recombination. These hypotheses can be tested by examining the evolutionary rates for sites...

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Share to Regulatory Sequences, Nucleic Acid

Source

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Identifiers

PMID: 10968778
DOI: 10.1086/303092
PMCID: PMC1287875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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