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Article

Characterizing the time dependency of human mitochondrial DNA mutation rate estimates.

Molecular biology and evolution - 1 Jan 2009

Henn Brenna M, Gignoux Christopher R, Feldman Marcus W, Mountain Joanna L

Abstract excerpt

Previous research has established a discrepancy of nearly an order of magnitude between pedigree-based and phylogeny-based (human vs. chimpanzee) estimates of the mitochondrial DNA (mtDNA) control region mutation rate. We characterize the time dependency of the human mitochondrial hypervariable region one mutation rate by generating 14 new phylogeny-based mutation rate estimates using within-human comparisons and...

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PMID: 18984905
DOI: 10.1093/molbev/msn244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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