Article
Genetic and biochemical analysis of glutathione-S-transferase in the oxygen defense system of Drosophila melanogaster.
Genome - 1 Dec 1993
Parkes T L, Hilliker A J, Phillips J P
Abstract excerpt
Aerobic organisms possess an array of enzymatic defense mechanisms against the toxic effects of active oxygen species. These include CuZn superoxide dismutase (CuZn SOD), catalase (CAT), and glutathione peroxidase (GPOX). Insects, however, lack an independent GPOX enzyme and instead rely on the activity of the more general detoxification enzyme, glutathione-S-transferase (GST), to carry out a peroxidase function....
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