Genetic and biochemical analysis of glutathione-S-transferase in the oxygen defense system of Drosophila melanogaster.

doi:10.1139/g93-134

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Article

Genetic and biochemical analysis of glutathione-S-transferase in the oxygen defense system of Drosophila melanogaster.

Genome - 1 Dec 1993

Parkes T L, Hilliker A J, Phillips J P

Abstract excerpt

Aerobic organisms possess an array of enzymatic defense mechanisms against the toxic effects of active oxygen species. These include CuZn superoxide dismutase (CuZn SOD), catalase (CAT), and glutathione peroxidase (GPOX). Insects, however, lack an independent GPOX enzyme and instead rely on the a...

Topics

Animals
Antioxidants
Drosophila melanogaster
Enzyme Induction
Female
Genes, Insect
Genetic Complementation Test
Glutathione
Glutathione Transferase
Male
Mutation
Paraquat
Reactive Oxygen Species
Superoxide Dismutase

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