Article
Low-activity allele of copper-zinc superoxide dismutase (CuZnSOD) in Drosophila increases paraquat genotoxicity but does not affect near UV radiation damage.
Genome - 1 Aug 2001
Vontas J G, Tsakas S C, Loukas M, Hemingway J
Abstract excerpt
Different types of mutations and DNA-damage profiles induced by near-UV radiation and the superoxide anion (O2-.) indicate separate lesions and (or) mechanisms of mutagenesis. Despite a wealth of data, it is still unclear whether variations in the activity levels of antioxidant enzymes naturally present in suboptimal concentrations are among the underlying causes of the increase of near UV radiation genotoxicity....
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