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Article

Phenotypic consequences of copper-zinc superoxide dismutase overexpression in Drosophila melanogaster.

Genome - 1 Dec 1990

Staveley B E, Phillips J P, Hilliker A J

Abstract excerpt

We report here the isolation of a tandem duplication of a small region of the third chromosome of Drosophila melanogaster containing the Cu-Zn superoxide dismutase (cSOD) gene. This duplication is associated with a dosage-dependent increase in cSOD activity. The biological consequences of hypermorphic levels of cSOD in genotypes carrying this duplication have been investigated under diverse conditions of oxygen...

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Identifiers

PMID: 1964925
DOI: 10.1139/g90-130

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