Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.

Molecular and cellular biology - 1 Feb 1994

Reveillaud I, Phillips J, Duyf B, Hilliker A, Kongpachith A, Fleming J E

Abstract excerpt

Null mutants for Cu/Zn superoxide dismutase (CuZnSOD) in Drosophila melanogaster are male sterile, have a greatly reduced adult life span, and are hypersensitive to paraquat. We have introduced a synthetic bovine CuZnSOD transgene under the transcriptional control of the D. melanogaster 5C actin promoter into a CuZnSOD-null mutant of D. melanogaster. This was carried out by P-element-mediated transformation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Cattle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Drosophila melanogaster

Share to Electrophoresis, Polyacrylamide Gel

Share to Isoenzymes

Share to Phenotype

Share to X Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 8289809
DOI: 10.1128/mcb.14.2.1302-1307.1994
PMCID: PMC358485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.PMID 8289809Read ↗

Transgenic analysis of the cSOD-null phenotypic syndrome in Drosophila.Semantic proximity Read ↗

Phenotypic consequences of copper-zinc superoxide dismutase overexpression in Drosophila melanogaster.Semantic proximity Read ↗

Genetic and biochemical analysis of glutathione-S-transferase in the oxygen defense system of Drosophila melanogaster.Semantic proximity Read ↗

What can flies tell us about copper homeostasis?Semantic proximity Read ↗

Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase.Semantic proximity Read ↗

Increased spontaneous DNA damage in Cu/Zn superoxide dismutase (SOD1) deficient Drosophila.Semantic proximity Read ↗

Genetic organization of the cSOD microregion of Drosophila melanogaster.Semantic proximity Read ↗

Genomic regions responsible for manganese superoxide dismutase regulation in Drosophila melanogaster.Semantic proximity Read ↗

Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone.Semantic proximity Read ↗

Cloning and expression analysis of Drosophila extracellular Cu Zn superoxide dismutase.Semantic proximity Read ↗

The four members of the Drosophila metallothionein family exhibit distinct yet overlapping roles in heavy metal homeostasis and detoxification.Semantic proximity Read ↗

Xenopus laevis Cu,Zn superoxide dismutase B cDNA sequence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.