Article
Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.
Molecular and cellular biology - 1 Feb 1994
Reveillaud I, Phillips J, Duyf B, Hilliker A, Kongpachith A, Fleming J E
Abstract excerpt
Null mutants for Cu/Zn superoxide dismutase (CuZnSOD) in Drosophila melanogaster are male sterile, have a greatly reduced adult life span, and are hypersensitive to paraquat. We have introduced a synthetic bovine CuZnSOD transgene under the transcriptional control of the D. melanogaster 5C actin...
Topics
- Animals
- Animals, Genetically Modified
- Cattle
- Crosses, Genetic
- Drosophila melanogaster
- Electrophoresis, Polyacrylamide Gel
- Female
- Fertility
- Infertility, Male
- Isoenzymes
- Longevity
- Male
- Phenotype
- Superoxide Dismutase
- X Chromosome