Genetic analysis of oxygen defense mechanisms in Drosophila melanogaster and identification of a novel behavioural mutant with a Shaker phenotype.

doi:10.1139/g96-094

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Article

Genetic analysis of oxygen defense mechanisms in Drosophila melanogaster and identification of a novel behavioural mutant with a Shaker phenotype.

Genome - 1 Aug 1996

Humphreys J M, Duyf B, Joiner M L, Phillips J P, Hilliker A J

Abstract excerpt

Mutants of Drosophila melanogaster that lack Cu/Zn superoxide dismutase or urate are hypersensitive to reactive oxygen species (ROS) generated in vivo by the redox-cycling agent paraquat. We have subsequently employed paraquat as a selective agent to identify adult viable mutants potentially defe...

Topics

Animals
Crosses, Genetic
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Drug Resistance
Ethyl Methanesulfonate
Female
Gene Expression Regulation
Genes, Lethal
Heterozygote
Insect Hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Longevity

Male

Membrane Proteins

Movement Disorders

Mutagenesis

Mutation

Source

Open in PubMed

Identifiers

PMID: 8776866
DOI: 10.1139/g96-094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8776866-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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