Article
Differential roles of tau class glutathione S-transferases in oxidative stress.
The Journal of biological chemistry - 4 Jun 2004
Kilili Kimiti G, Atanassova Neli, Vardanyan Alla, Clatot Nicolas, Al-Sabarna Khaled, Kanellopoulos Panagiotis N, Makris Antonios M, Kampranis Sotirios C
Abstract excerpt
The plant glutathione S-transferase BI-GST has been identified as a potent inhibitor of Bax lethality in yeast, a phenotype associated with oxidative stress and disruption of mitochondrial functions. Screening of a tomato two-hybrid library for BI-GST interacting proteins identified five homologous Tau class GSTs, which readily form heterodimers between them and BI-GST. All six LeGSTUs were found to be able to...
Topics
- Amino Acid Sequence
- Catalysis
- Dimerization
- Dose-Response Relationship, Drug
- Glutathione
- Glutathione Disulfide
- Glutathione Transferase
- Hydrogen-Ion Concentration
- Kinetics
- Solanum lycopersicum