Article
A mutation data matrix for transmembrane proteins.
FEBS letters - 21 Feb 1994
Jones D T, Taylor W R, Thornton J M
Abstract excerpt
The widely used Mutation Data Matrix (MDM), is an amino acid comparison matrix calculated from a study of the exchange probabilities (or odds) derived from an analysis of the evolutionary changes seen in groups of very similar proteins. In this work, a mutation data matrix is calculated for membr...
Topics
- Amino Acid Sequence
- Amino Acids
- Biological Evolution
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Probability
- Protein Structure, Secondary