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Article

Evolutionary Influenced Interaction Pattern as Indicator for the Investigation of Natural Variants Causing Nephrogenic Diabetes Insipidus.

Computational and mathematical methods in medicine - 1 Jan 2015

Grunert Steffen, Labudde Dirk

Abstract excerpt

The importance of short membrane sequence motifs has been shown in many works and emphasizes the related sequence motif analysis. Together with specific transmembrane helix-helix interactions, the analysis of interacting sequence parts is helpful for understanding the process during membrane protein folding and in retaining the three-dimensional fold. Here we present a simple high-throughput analysis method for...

Topics

Algorithms
Aquaporin 2
Arginine Vasopressin
Biomarkers
Computational Biology
Computer Graphics
DNA Mutational Analysis
Databases, Protein
Diabetes Insipidus, Nephrogenic
Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Imaging, Three-Dimensional

Mutation

Phosphorylation

Pituitary Gland

Protein Conformation

Protein Folding

Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 26180540
DOI: 10.1155/2015/641393
PMCID: PMC4477446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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