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Article

Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins.

BMC bioinformatics - 27 Apr 2011

Olivera-Nappa Alvaro, Andrews Barbara A, Asenjo Juan A

Abstract excerpt

BACKGROUND: Functionally relevant artificial or natural mutations are difficult to assess or predict if no structure-function information is available for a protein. This is especially important to correctly identify functionally significant non-synonymous single nucleotide polymorphisms (nsSNPs) or to design a site-directed mutagenesis strategy for a target protein. A new and powerful methodology is proposed to...

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Identifiers

PMID: 21524307
DOI: 10.1186/1471-2105-12-122
PMCID: PMC3123232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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