Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial adenomatous polyposis: from bedside to benchside.

American journal of clinical pathology - 1 May 1998

O'Sullivan M J, McCarthy T V, Doyle C T

Abstract excerpt

Familial adenomatous polyposis (FAP) is a dominantly inherited cancer-predisposition syndrome with an incidence of between 1:17,000 and 1:5,000. The condition has been causally linked to mutation of the adenomatous polyposis coli (APC) gene located at 5q21. Virtually all mutations in the APC gene are truncating mutations, resulting in loss of function of the APC protein. Spontaneous germline mutation of this gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Chromosomes, Human, Pair 5
Share to Cytoskeletal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to APC gene

Share to FAP gene

Share to Genes, APC

Share to Mutation

Share to Trans-Activators

Source

Identifiers

PMID: 9576568
DOI: 10.1093/ajcp/109.5.521

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial adenomatous polyposis: from bedside to benchside.PMID 9576568Read ↗

Familial adenomatous polyposis.Semantic proximity Read ↗

Familial Adenomatous PolyposisSemantic proximity Read ↗

Genotype-phenotype correlations at the adenomatous polyposis coli (APC) gene.Semantic proximity Read ↗

The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk managementSemantic proximity Read ↗

APC-associated polyposis conditionsSemantic proximity Read ↗

Colorectal adenomatous polyposis syndromes: Genetic determinism, clinical presentation and recommendations for care.Semantic proximity Read ↗

[Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].Semantic proximity Read ↗

Familial adenomatous polyposis: The practical applications of clinical and molecular screening.Semantic proximity Read ↗

Adenomatous Polyposis Coli Gene Polyposis-Related Syndromes.Semantic proximity Read ↗

Novel strategies for comprehensive mutation screening of the APC gene.Semantic proximity Read ↗

An update of the variant spectrum of the APC gene in Iranian familial adenomatous polyposis patients.Semantic proximity Read ↗

[From gene to disease; the APC gene and familial adenomatous polyposis coli].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.