Article
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast.
Nature - 3 Mar 1994
Wang Z, Svejstrup J Q, Feaver W J, Wu X, Kornberg R D, Friedberg E C
Abstract excerpt
Nucleotide-excision repair (NER) is an important cellular defence mechanism against mutagenesis and carcinogenesis. The essential yeast genes RAD3 (ref. 2) and SSL2 (RAD25), homologues of the human xeroderma pigmentosum genes XPD and XPB respectively, have been implicated in NER in yeast. The pro...
Topics
- Acetoxyacetylaminofluorene
- Adenosine Triphosphatases
- DNA Damage
- DNA Helicases
- DNA Repair
- DNA, Fungal
- Fungal Proteins
- Genetic Complementation Test
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- TATA-Binding Protein Associated Factors
- Transcription Factor TFIID
- Transcription Factor TFIIH
- Transcription Factors
- Transcription Factors, TFII
- Transcription, Genetic