Article
Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain.
Journal of virology - 1 Mar 1994
Ramakrishnan R, Fink D J, Jiang G, Desai P, Glorioso J C, Levine M
Abstract excerpt
Competitive quantitative PCRs were used to examine the consequences of stereotactically injecting a highly attenuated herpes simplex virus type 1 mutant into rat brains. This mutant virus, designated RR1CAT/RR2lacZ, was engineered so that coding sequences of the genes UL39 and UL40 specifying the...
Topics
- Animals
- Base Sequence
- DNA, Viral
- Genome, Viral
- Herpes Simplex
- Herpesvirus 1, Human
- Hippocampus
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA, Messenger
- RNA, Viral
- Rats
- Rats, Sprague-Dawley
- Ribonucleotide Reductases